Association of FTO rs9939609 with Obesity
نویسندگان
چکیده
منابع مشابه
Association of FTO rs9939609 SNP with Obesity and Obesity- Associated Phenotypes in a North Indian Population.
OBJECTIVES Obesity is a common disorder that has a significant impact on morbidity and mortality. Twin and adoption studies support the genetic influence on variation of obesity, and the estimates of the heritability of body mass index (BMI) is significantly high (30 to 70%). Variants in the fat mass and obesity-associated (FTO) gene have been associated with obesity and obesity-related phenoty...
متن کاملAssociation between overweight and obesity in schoolchildren with rs9939609 polymorphism (FTO) and family history for obesity.
OBJECTIVE To determine the association between overweight/obesity in schoolchildren with FTO rs9939609 polymorphism (fatmass and obesity associated) and family history of obesity. METHODS Cross-sectional study comprising a sample of 406 children aged 7-17 years in a city in southern Brazil. Overweight/obesity in schoolchildren was assessed by body mass index (BMI), and family history of obesi...
متن کاملEducation modulates the association of the FTO rs9939609 polymorphism with body mass index and obesity risk in the Mediterranean population.
OBJECTIVE To define whether the rs9939609 FTO (fat mass and obesity associated) single nucleotide polymorphism (SNP) is associated with anthropometric measurements and its modulation by educational level in a Mediterranean population. METHODS We studied 3 independent adult samples: a random sample (n = 1580) from the general population (GP), obese hospital patients (OHP) (n = 203) and elderly...
متن کاملThe association of the FTO rs9939609 polymorphism with obesity and metabolic risk factors for cardiovascular diseases in Polish children.
The phenomenon of excessive body mass increase in the general population of children and adults in the past few decades and has been attributed to environmental changes, especially when superimposed on a predisposing genetic background. The fat mass and obesity-associated (FTO) gene has recently become one of the most extensively investigated genes associated with body mass. The aim of the stud...
متن کاملFTO polymorphism (RS9939609) and BED in patients with morbid obesity for evaluation towards bariatric surgery
Background Obesity is a major health problem in the twenty-first century. Recent research shows that, among people with severe obesity, there is a sub-population that does not respond to behavioral treatment for weight loss. This group presents a type of eating disorder known as Binge Eating Disorder (BED). Recent studies indicate a link between obesity in adults and the rs9939609 polymorphism ...
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ژورنال
عنوان ژورنال: Medical Principles and Practice
سال: 2018
ISSN: 1011-7571,1423-0151
DOI: 10.1159/000490495